August 19th, 2015 by Charlie Blackburn | NAACCReview Home Leave a comment

ObstetricsandGynOne in three women diagnosed with ovarian cancer will live for 10 years or more, according to a new study published in the Journal of Obstetrics and Gynecology — good news, considering ovarian cancer has long been considered highly fatal.

More than 20,000 women are diagnosed with ovarian cancer and 14,000 women will die from the disease each year, according to the Centers for Disease Control and Prevention.

“The perception that almost all women will die of this disease is not correct,” Rosemary Cress, lead author of the paper, told UC Davis Health System. “This information will be helpful to physicians who first diagnose these patients and the obstetricians/gynecologists who take care of them after they receive treatment from specialists.”

The researchers tracked survival information for more than 11,000 women in California diagnosed with the most common kind of ovarian cancer between 1994 and 2001, the majority of whom were white and more than 50 years old.

While most patients lived less than five years after their diagnosis, 31 percent lived longer than 10 years, the threshold at which women are considered long-term survivors.

Read Full Article (Excerpt of Article by Erin Schumaker from the Huffington Post

rosemary-cress-150x150Comments by:
Rosemary Cress, Ph.D, Co-Investigator, Cancer Registry of Greater California (NAACCR Committee Member)

Patients and physicians commonly perceive ovarian cancer as a highly fatal disease. Since about 60% of patients present with advanced stage disease, the prognosis is often poor. Yet some women are known to survive for many years after diagnosis. Dr. Rosemary Cress of the Public Health Institute’s Cancer Registry of Greater California, a SEER registry, collaborated with researchers from UC Davis to compare characteristics of women who survived more than 10 years after diagnosis to those with shorter survival using patients identified through the California Cancer Registry. Patients diagnosed between 1994 and 2001, with follow up through 2011, were included. Of 11,541 women identified, 3,582 (31%) survived over 10 years. Long-term survivors were more likely to be younger and to have early stage, non-serous, and lower grade tumors, but a substantial number of survivors were older or had other characteristics of poor prognosis. Nearly a third of long term survivors had Stage III or IV cancers.

Survival for all stages is slowly improving possibly because of advances in treatment such as improved surgical methods and intraperitoneal chemotherapy. There also is likely some biologic variability among tumors that needs to be further understood. Further research is needed to include more detailed treatment information as well as genomic analysis of tumor tissue.

Results of this study provide hope to newly diagnosed patients and can be useful for counseling patients that although ovarian cancer is a dangerous cancer it is not uniformly fatal, even at an advanced stage.

An article based on the study has been published in the Journal of Obstetrics and Gynecology. The article has produced a great deal of media attention and has been featured in MSN and the Huffington Post. The results of this study were newsworthy because most studies do not have the resources to follow patients for a long period of time after diagnosis. Once again, such important research could not be accomplished without the careful and high quality work of hospital registrars and state and regional registry staff.

The opinions expressed in this article are those of the authors and may not represent the official positions of NAACCR.



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